Mechanism
Link measurable immune and haematological signals to plausible biology.
Research · Biochemistry · Systems biology
Questions first.
Methods second.
My work sits between experimental biochemistry, infectious-disease biology and quantitative thinking. I am especially interested in questions that matter in African settings and can be translated into useful evidence.
Current direction
Immunity, malaria and the first months of life.
A developing MSc research direction asks how maternally acquired anti-CSP antibodies, fetal-haemoglobin trajectories and infant malaria outcomes interact in the era of R21/Matrix-M vaccination. The emphasis is on a biologically interpretable question, careful longitudinal analysis and reproducible workflows.
Time
Treat repeated measurements as trajectories, not isolated snapshots.
Reproducibility
Make data decisions and computational steps transparent enough to rerun.
Research portfolio
A connected set of experimental and computational projects.
Dynamical modelling of host–pathogen interactions
Ordinary differential-equation models for pathogen growth, immune response, equilibrium behaviour and biological interpretation of parameters.
ODEssystems biologyPython
Medicinal-plant phytochemistry & antibacterial activity
Plant extraction, phytochemical profiling and antibacterial assays, connecting measured inhibition to candidate secondary metabolites.
phytochemistrymicrobiologyspectrophotometry
RNA-seq analysis notes
An educational Linux workflow from raw FASTQ quality control through trimming, splice-aware alignment and gene-level read quantification.
RNA-seqLinuxreproducibility
Selected publications
Published work.
Use the DOI links for the publication record. Citation details below mirror the journal records.
Phytochemical Analysis and Antibacterial Activity of Aloe Vera Leaf Extracts Across Different Leaf Ages
Alule Robert & Isabirye Isaac · Journal of Diseases and Medicinal Plants, 10(4), 60–68.
Phytochemistry and Antibacterial Activity of Platycerium coronarium Leaf Extracts
Alule Robert, Isabirye Isaac & Walugembe Joel · Journal of Diseases and Medicinal Plants, 9(4), 137–147.
For collaborators & students
Good science gets stronger when it is shared.
For research discussions, student project mentorship or teaching-resource collaboration, get in touch with a clear question and a short description of what you are working on.